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Federal contractor profile

SPERO THERAPEUTICS, INC.

UEI NX34PL7NZW24CAGE 7SK81

Active
Small Business

Overview

Legal name
SPERO THERAPEUTICS, INC.
Registered location
CAMBRIDGE, MA, USA
Primary NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Latest award activity
Jul 20, 2026
Read company summary

SPERO THERAPEUTICS, INC. is associated with UEI NX34PL7NZW24 and CAGE 7SK81 in public federal records. AcornBids currently links 2 prime awards totaling $59.7M in obligations to this entity. Its largest recorded federal customer by obligations is Department of Health and Human Services. Its recorded federal awards include work classified as Research and Development in Biotechnology (except Nanobiotechnology); Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). These categories describe the loaded award records, not a complete list of company capabilities. Its primary SAM.gov NAICS is 541715 (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)). Its public SAM.gov registration lists CAMBRIDGE, MA, USA.

At a glance

Lifetime prime obligations$59.7M
Prime awards2
Awards with future end dates0
Top-agency concentration
Not available

Why this customer concentration

Detailed agency totals are not available in this stored profile.

Largest positive coded-agency total ÷ all positive coded-agency totals × 100

Missing data is shown as unavailable.

Prime contract obligations across loaded award records. Obligations are not revenue or contract ceilings. Summary updated Oct 13, 2026. Refresh pending; these totals may be out of date.

Business information

Public SAM.gov registration details.

Legal name
SPERO THERAPEUTICS, INC.
UEI
NX34PL7NZW24
CAGE
7SK81
Registered address
14TH FLOOR, CAMBRIDGE, MA, 02139, USA
Registration status
Active
Primary NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
SAM activation
Jul 6, 2026
Initial registration
Jan 13, 2017
Entity start
Dec 12, 2013
SAM updated
Jul 6, 2026
Registration expires
Jul 2, 2027
Fiscal year end
Dec 31
Place of incorporation
DE, USA

View SAM.gov source

Research brief

Source facts

  • Loaded prime-award records link 2 awards and $59,697,655 in reported obligations to this legal entity. Source
  • Recorded awards include Research and Development in Biotechnology (except Nanobiotechnology) (NAICS 541714); this classification is not proof of every company capability. Source
  • An example award describes: TO ADVANCE CLINICAL AND NON-CLINICAL DEVELOPMENT OF AN ANTIBIOTIC CANDIDATE. Source

Federal award analysis

Net transaction obligations by federal fiscal period.

Selected transaction obligations$59.7M
Prime contracts
$15.7MFY2018$2.5MFY2019$0FY2020$2.1MFY2021$12.9MFY2022$5.0MFY2023$15.8MFY2024$6.4MFY2025$-537.2KFY2026

Reported transaction obligations by federal fiscal period; includes deobligations. Missing transactions are not estimated. Coverage: 2 of 2 selected awards. Select a period to explore its awards.

Explore funding & geography →View quarterly funding

Recent federal awards

Prime contract awards. Select an award to review its history and source evidence.

Award / descriptionAwarding agencyObligationsStart dateEnd date
75N93021C00022TO ADVANCE CLINICAL AND NON-CLINICAL DEVELOPMENT OF AN ANTIBIOTIC CANDIDATE.Department of Health and Human Services$10.5MMay 17, 2021Apr 4, 2025
75A50118C00015IGF::OT::IGFDepartment of Health and Human Services$49.2MJul 12, 2018Jul 6, 2026
Explore, filter and export all awards →SubcontractsGrants & subgrants

Registration, certifications & contacts

Registration evidenceDate
SAM updatedJul 6, 2026
Source loadedSep 26, 2026
Initial registrationJan 13, 2017
Entity startDec 12, 2013

Registration classifications: Small Business. These are separate from the reported certificates above.

IndustryReported size status
541714 — Research and Development in Biotechnology (except Nanobiotechnology)Not reported
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)Not reported
ContactRolePublished contact methodsEvidenceSource date
AKASH JAINGovernment businessContact method not publishedSAM registrationNot available
AKASH JAINElectronic businessContact method not publishedSAM registrationNot available
Registered industries
  • 541714 — Research and Development in Biotechnology (except Nanobiotechnology)
  • 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Registration classifications and published certificates do not by themselves establish eligibility for a particular solicitation. View SAM source

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Explore the customer, work and award-size evidence behind each match.

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1 shared agency customer(s); Shared work: 541714 — Research and Development in Biotechnology (except Nanobiotechnology), 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Counts and amounts describe sampled matching awards, not the company’s full history.
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THE JOHNS HOPKINS UNIVERSITY

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7 awards

REGENTS OF THE UNIVERSITY OF MICHIGAN

1 shared agency customer(s); Shared work: 541714 — Research and Development in Biotechnology (except Nanobiotechnology), 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Counts and amounts describe sampled matching awards, not the company’s full history.
3 awards

UNIVERSITY OF WASHINGTON

1 shared agency customer(s); Shared work: 541714 — Research and Development in Biotechnology (except Nanobiotechnology), 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Counts and amounts describe sampled matching awards, not the company’s full history.
3 awards

GOVERNMENT SCIENTIFIC SOURCE INC

1 shared agency customer(s); Shared work: 541714 — Research and Development in Biotechnology (except Nanobiotechnology), 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Counts and amounts describe sampled matching awards, not the company’s full history.
3 awards

RESEARCH TRIANGLE INSTITUTE

1 shared agency customer(s); Shared work: 541714 — Research and Development in Biotechnology (except Nanobiotechnology), 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Counts and amounts describe sampled matching awards, not the company’s full history.
10 awards

About SPERO THERAPEUTICS, INC.

What products and services appear in its federal awards?

Recorded award industries: 541714 — Research and Development in Biotechnology (except Nanobiotechnology); 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

Recorded products and services: AN13 — HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT; AN11 — HEALTH R&D SERVICES; HEALTH CARE SERVICES; BASIC RESEARCH.

Examples from recent award records:

These records describe federal award work, not every company capability. Review the award evidence.

Where is the company registered?

14TH FLOOR, CAMBRIDGE, Massachusetts 02139, United States

Registered location from SAM.gov; award performance locations may differ.

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Data coverage and methodology

Sources: SAM.gov registration, USAspending awards and transactions, and linked supporting records. Prime contract obligations, IDV ceilings and assistance amounts are kept separate. Missing records are not zero activity. Company claims are labeled separately. Recompete signals are rule-based scores out of 100. Positioning windows are AcornBids estimates.

Disclosed relationships only. Missing records do not establish that a contractor has no partners. Ambiguous parent award identifiers are excluded.

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